KRAS G12C inhibitor 27
KRAS G12C inhibitor 27 is a KRAS G12C inhibitor with antitumor effects (WO2021109737) [1].
Product Specifications
CAS Number
[2648584-51-2]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-27.html
Solubility
10 mM in DMSO
Smiles
N#CC[C@@H]1N(C(C(F)=C)=O)CCN(C2=C(CO[C@@H](C3=CC=CC=C3C(F)(F)F)C4)C4=NC(OC[C@H]5N(C)CCC5)=N2)C1
Molecular Formula
C29H32F4N6O3
Molecular Weight
588.60
References & Citations
[1]Zusheng Xu, et al. Oxygen-containing heterocyclic compound, preparation method and application thereof. WO2021109737A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
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