KRAS G12C inhibitor 27

[2648584-51-2]

12352005

Ras

Reference compound

GPCR/G Protein; MAPK/ERK Pathway

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/kras-g12c-inhibitor-27.html

10 mM in DMSO

N#CC[C@@H]1N(C(C(F)=C)=O)CCN(C2=C(CO[C@@H](C3=CC=CC=C3C(F)(F)F)C4)C4=NC(OC[C@H]5N(C)CCC5)=N2)C1

C29H32F4N6O3

588.60

[1]Zusheng Xu, et al. Oxygen-containing heterocyclic compound, preparation method and application thereof. WO2021109737A1.

Room temperature

Reference compound1

No Development Reported

K-Ras