Pan-RAF kinase inhibitor 1
Pan-RAF kinase inhibitor 1 is a potent inhibitor of Pan-RAF kinase. Pan-RAF kinase inhibitor 1 regulates MAPK signaling by inhibiting RAF kinase, thereby exerting an effect on the proliferation of RAS-mutant tumor cells. Pan-RAF kinase inhibitor 1 has the potential for the research of cancer diseases (extracted from patent WO2021110141A1, compound 16B) [1].
Product Specifications
CAS Number
2648838-76-8
UNSPSC
12352005
Target
Raf
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pan-raf-kinase-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
OCCOC1=NC([C@]23[C@](COC3)([H])C2)=CC(C4=CC(NC(C5=CC=NC(C(F)(F)F)=C5)=O)=CC=C4C)=C1
Molecular Formula
C26H24F3N3O4
Molecular Weight
499.48
References & Citations
[1]Zhaozhong Ding, et al. Biaryl Compounds of Pan-RAF Kinase Inhibitors. Patent WO2021110141A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
TGF-beta (1D11.16.8), CF770 conjugate, 0.1mg/mL
MUC18 / Mucin 18 / CD146 (OJ79c), CF568 conjugate, 0.1mg/mL
