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ERK1/2 inhibitor 8

ERK1/2 inhibitor 8 is a potent ERK inhibitor with an IC50 of 0.48 nM for ERK2 (WO2021110168A1, WX007) [1].

Product Specifications

CAS Number

2648368-43-6

UNSPSC

12352005

Target

ERK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/erk1-2-inhibitor-8.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(C3(COC3)N1CC4=CC(Cl)=CC=C4)SC(C5=C(C)C=NC(NC6=CC=NN6C)=N5)=N2

Molecular Formula

C23H20ClN7O2S

Molecular Weight

493.97

References & Citations

[1]WO2021110168A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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