What is the catalog number for LIMK-IN-1?

The catalog number for LIMK-IN-1 is HY-14227.

What sizes are available for LIMK-IN-1?

LIMK-IN-1 is available in the following size(s): 2 mg.

Is LIMK-IN-1 in stock?

LIMK-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures LIMK-IN-1?

LIMK-IN-1 is manufactured by QuantiMol.

What is the estimated delivery time for LIMK-IN-1?

Estimated delivery time for LIMK-IN-1 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for LIMK-IN-1?

The safety data sheet for LIMK-IN-1 is available here: http://file.medchemexpress.com/batch_PDF/HY-14227/LIMK-IN-1-SDS-MedChemExpress.pdf.

LIMK-IN-1

LIMK-IN-1 (Compound 14) is a LIMK1/2 inhibitor (IC50: 0.5 nM and 0.9 nM respectively) . LIMK-IN-1 can be used for research of ocular hypertension and associated glaucoma[1].

Product Specifications

CAS Number

1116571-01-7

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

LIM Kinase (LIMK) ; ROCK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/limk-in-1.html

Purity

99.33

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

CC1=CNC2=NC=NC(N3C[C@H](C)N(/C(NC4=CC=CC(Br)=C4)=N\C#N)CC3)=C21

Molecular Formula

C20H21BrN8

Molecular Weight

453.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Harrison BA, et.al. Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J Med Chem. 2009 Nov 12;52 (21) :6515-8. |[2]Harrison BA, et al. Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J Med Chem. 2009 Nov 12;52 (21) :6515-8.