TRPA1-IN-1
TRPA1-IN-1 is a potent, selective, and orally bioavailable TRPA1 small molecule antagonist.
Product Specifications
CAS Number
2376824-92-7
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/trpa1-in-1.html
Solubility
10 mM in DMSO
Smiles
CN1C=NC2=C1C(N(C=N2)CC3=NC([C@@H]4CO[C@H](C4)C5=CC=C(C=C5)Cl)=NO3)=O
Molecular Formula
C19H17ClN6O3
Molecular Weight
412.83
References & Citations
[1]Terrett JA, et al. Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy. J Med Chem. 2021 Apr 8;64 (7) :3843-3869.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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