T988C
Product Specifications
CAS Number
823802-57-9
UNSPSC Description
T988C is a heptacyclic epidithiodioxopiperazine (ETP) natural product. T988C shows strong cytotoxicity to cultured P388 leukemia cells[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/t988c.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@]2(C3=CNC4=CC=CC=C34)[C@@](NC5=CC=CC=C52)([H])N6[C@@]17C(N([C@](C6=O)(SS7)CO)C)=O
Molecular Weight
480.56
References & Citations
[1]DeLorbe JE, et al. General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A. J Am Chem Soc. 2013 Mar 13;135(10):4117-28. |[2]Feng Y, et al. Novel cytotoxic thiodiketopiperazine derivatives from a Tilachlidium sp. J Nat Prod. 2004 Dec;67(12):2090-2.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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