NSD3-IN-3
NSD3-IN-3 is a potent NSD3 inhibtor with an IC50 value of 1.86 μM. NSD3-IN-3 has anticancer activity and significantly inhibits the growth and proliferation of non-small cell lung cancer cell line H460[1].
Product Specifications
CAS Number
[445416-12-6]
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsd3-in-3.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
S=C1NC2=C(N)N=CN=C2N1CCOC3=CC=C(OCC)C=C3
Molecular Formula
C15H17N5O2S
Molecular Weight
331.39
References & Citations
[1]Kong Ren, et al. Application of compound B2 as histone methyltransferase NSD3 inhibitor: China, CN109223795[P].2019-01-18.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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