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NSD3-IN-3

NSD3-IN-3 is a potent NSD3 inhibtor with an IC50 value of 1.86 μM. NSD3-IN-3 has anticancer activity and significantly inhibits the growth and proliferation of non-small cell lung cancer cell line H460[1].

Product Specifications

CAS Number

445416-12-6

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nsd3-in-3.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

S=C1NC2=C(N)N=CN=C2N1CCOC3=CC=C(OCC)C=C3

Molecular Formula

C15H17N5O2S

Molecular Weight

331.39

References & Citations

[1]Kong Ren, et al. Application of compound B2 as histone methyltransferase NSD3 inhibitor: China, CN109223795[P].2019-01-18.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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