NSD3-IN-2
NSD3-IN-2 is a potent NSD3 inhibitor with an IC50 value of 17.97 μM. NSD3-IN-2 inhibits the growth and proliferation of non-small cell lung cancer cell lines H460, H1299 and H1650 with anti-cancer activity[1].
Product Specifications
CAS Number
[675190-57-5]
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsd3-in-2.html
Solubility
10 mM in DMSO
Smiles
S=C1NC2=C(N)N=CN=C2N1CCOC3=C4C=CC=CC4=CC=C3
Molecular Formula
C17H15N5OS
Molecular Weight
337.40
References & Citations
[1]Piao Lianhua, et al. Application of compound C6 as histone methyltransferase NSD3 inhibitor: China, CN109223794[P].2019-01-18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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