Beauverolide Ja
Beauverolide Ja, a cyclotetradepsipeptide, is a potent calmodulin (CaM) inhibitor with a Kd of 0.078 μM and a Ki of 0.39 μM for Ca2+-CaM. Beauverolide Ja is a secondary metabolite of Isaria fumosorosea[1].
Product Specifications
CAS Number
76265-41-3
UNSPSC
12352005
Target
Calmodulin; Endogenous Metabolite
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/beauverolide-ja.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](C(N[C@](C(OC(CC(N1)=O)C(C)CCCC)=O)([H])[C@@H](C)CC)=O)CC2=CC=CC=C2)[C@@H]1CC3=CNC4=CC=CC=C34
Molecular Formula
C35H46N4O5
Molecular Weight
602.76
References & Citations
Isaria fumosoroseaIsaria farinose
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Microbial Metabolite
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