Inophyllum B

Inophyllum B ((+) -Inophyllum B) is a potent HIV Reverse Transcriptase inhibitor with an IC50 value of 38 nM. Inophyllum B inhibits HIV-1 (IC50=1.4 μM) in vitro cell culture. Inophyllum B can be isolated from the acetone extract of the giant African snail, Achatina fulica[1].

Product Specifications

CAS Number

[41135-06-2]

Product Name Alternative

(+) -Inophyllum B

UNSPSC

12352005

Target

HIV; Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/inophyllum-b.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]1C2=C(O[C@@H]([C@H]1C)C)C(C=CC(C)(O3)C)=C3C(C(C4=CC=CC=C4)=C5)=C2OC5=O

Molecular Formula

C25H24O5

Molecular Weight

404.46

References & Citations

[1]Patil AD, et al. The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn. J Med Chem. 1993 Dec 24;36 (26) :4131-8.