(R) -IDHP

(R) -IDHP is an isomer of IDHP, a salvia metabolite that exerts vasorelaxant effects by inhibiting Ca2+ release and Ca2+ inward flow in voltage-dependent and receptor-operated calcium channels in vascular smooth muscle cells. IDHP is used in studies of cardiovascular disease[1].

Product Specifications

CAS Number

[950665-05-1]

UNSPSC

12352005

Target

Calcium Channel

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/r-idhp.html

Solubility

10 mM in DMSO

Smiles

CC(C)OC([C@H](O)CC1=CC(O)=C(C=C1)O)=O

Molecular Formula

C12H16O5

Molecular Weight

240.25

References & Citations

[1]MingChen, et al. Efficient and practical asymmetric synthesis of isopropyl (R) -3- (3′,4′-dihydroxyphenyl) -2-hydroxypropanoate and its enantiomer.Tetrahedron: Asymmetry