PRT543
PRT543 is a PRMT5 inhibitor to research cancer, sickle cell, and hereditary persistence of foetal hemoglobin (HPFH) mutations.
Product Specifications
CAS Number
[2278356-90-2]
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt5-in-14.html
Solubility
10 mM in DMSO
Smiles
O[C@@]1(C)[C@@H](O)[C@H](N2C3=NC=NC(N)=C3C=C2)O[C@@H]1[C@H](O)C4=CC=C(Cl)C(Cl)=C4
Molecular Formula
C18H18Cl2N4O4
Molecular Weight
425.27
References & Citations
[1]Machacek M, et al. Prmt5 inhibitors. WO2020033285A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PRMT5
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