ITK/TRKA-IN-1

ITK/TRKA-IN-1 is a dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA) with an IC50 value of 1.0 nM and 96 % inhibition, respectively.

Product Specifications

CAS Number

2655557-54-1

UNSPSC

12352005

Target

Itk

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/itk-trka-in-1.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12CC3=C(C(C4=NC5=C(N4)C=C(C(N(C([C@@H](N6CCOCC6)C)=O)C)=C5)C)=NN3)C[C@@H]1C2(F)F

Molecular Formula

C25H30F2N6O2

Molecular Weight

484.54

References & Citations

[1]Bagley SW, et al. Benzimidazole Derivatives. WO2021124155A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

More Discoveries

Explore Other Products

Browse additional items from our catalog

MBS9912596-01 48 Well

Camel Ras-Related Protein Ral-A (RALA) ELISA Kit

View Details

MBS9912596-02 96 Well

Camel Ras-Related Protein Ral-A (RALA) ELISA Kit

View Details

MBS9912596-03 5x 96 Well

Camel Ras-Related Protein Ral-A (RALA) ELISA Kit

View Details

MBS9912596-04 10x 96 Well

Camel Ras-Related Protein Ral-A (RALA) ELISA Kit

View Details

MBS1210658-01 0.02 mg (E-Coli)

Recombinant Rickettsia rickettsii Dihydrodipicolinate synthase (dapA)

View Details

MBS1210658-02 0.02 mg (Yeast)

Recombinant Rickettsia rickettsii Dihydrodipicolinate synthase (dapA)

View Details