PPO-IN-1
PPO-IN-1 is a potent protoporphyrinogen IX oxidase (PPO) inhibitor with a Ki value of 2.5 nM. PPO-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
2763288-69-1
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ppo-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C)C2=C(C=CS2)C(N1C3=C(F)C=C(C(N4CC#C)=C3)OC(F)(F)C4=O)=O
Molecular Formula
C18H10F3N3O4S
Molecular Weight
421.35
References & Citations
[1]Wang DW, et al. Discovery of a Potent Thieno[2,3-d]pyrimidine-2,4-dione-Based Protoporphyrinogen IX Oxidase Inhibitor through an In Silico Structure-Guided Optimization Approach. J Agric Food Chem. 2021 Nov 19.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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