BRD4-IN-2

BRD4-IN-2 is a bromodomain BRD4 inhibitor with an IC50 value of 9.9 nM.

Product Specifications

CAS Number

[2679925-55-2]

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/brd4-in-2.html

Solubility

10 mM in DMSO

Smiles

CNC(N1N=C(C2=C(C[C@@H]1C)C=C(C(OC)=C2)OC)C3=CC=C(C=C3)N4CCN(CC4)C(COCCOCC(NC5=C6C(N(C(C6=CC=C5)=O)C7CCC(NC7=O)=O)=O)=O)=O)=O

Molecular Formula

C43H48N8O11

Molecular Weight

852.89

References & Citations

[1]Sabnis RW. Substituted 2,3-Benzodiazepines Derivatives as Bromodomain BRD4 Inhibitors. ACS Med Chem Lett. 2021 Sep 28;12 (10) :1530-1531.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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