MMV674850
MMV674850 is potent against asexual stage parasites at 2.7 and 4.5 nM and preferentially targets early-stage gametocytes (early-stage gametocyte: IC50 4.5 ± 3.6 nM; late-stage gametocyte: IC50 28.7 ± 0.2 nM) .
Product Specifications
CAS Number
1820874-51-8
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mmv674850.html
Solubility
10 mM in DMSO
Smiles
CS(C(C=C1)=CC=C1C(C=N2)=C(N2C=C3)C=C3C4=CC(S(C5CC5)(=O)=O)=CC=C4)(=O)=O
Molecular Formula
C23H20N2O4S2
Molecular Weight
452.55
References & Citations
[1]Niemand J, et al. Chemogenomic Fingerprints Associated with Stage-Specific Gametocytocidal Compound Action against Human Malaria Parasites. ACS Infect Dis. 2021 Oct 8;7 (10) :2904-2916.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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