MGluR5 modulator 1

MGluR5 modulator 1 is a mGluR5 positive allosteric modulator. mGluR5 modulator 1 can be used for the research of the schizophrenia and cognitive impairments[1].

Product Specifications

CAS Number

[1261171-52-1]

UNSPSC

12352005

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mglur5-modulator-1.html

Solubility

10 mM in DMSO

Smiles

FC1=CC(Cl)=CC=C1N2CCN(C(COCC3=CC=NC=C3)=O)CC2

Molecular Formula

C18H19ClFN3O2

Molecular Weight

363.81

References & Citations

[1]Arsova A, et al. Positive Allosteric Modulators of Metabotropic Glutamate Receptor 5 as Tool Compounds to Study Signaling Bias. Mol Pharmacol. 2021 May;99 (5) :328-341.