MT-134
MT-134 is a SkMII-specific inhibitor and has excellent exposure in muscles.
Product Specifications
CAS Number
2968308-52-1
UNSPSC
12352005
Target
Myosin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mt-134.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@]2(O)C(N(C3=CN=C4C(OC(C)=N4)=C3)CC2)=NC5=C1C=C(C)C=C5
Molecular Formula
C19H16N4O3
Molecular Weight
348.36
References & Citations
[1]Radnai L, et al. Discovery of Selective Inhibitors for In Vitro and In Vivo Interrogation of Skeletal Myosin II. ACS Chem Biol. 2021 Nov 19;16 (11) :2164-2173.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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