PCSK9 ligand 1
PCSK9 ligand 1 is a selective proprotein convertase substilisin-like/kexin type 9 (PCSK9) ligand. PCSK9 ligand 1 does not affect PCSK9 function[1].
Product Specifications
CAS Number
2215931-60-3
UNSPSC
12352005
Target
PCSK9
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pcsk9-ligand-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NC=CS1)C[C@@]2(C3=CC(OC4=CC(F)=C(C5=CC=C(C=C5)C(O)=O)C=C4)=C(OCC6CCCCO6)C=C3CCN2)C
Molecular Formula
C34H34FN3O6S
Molecular Weight
631.71
References & Citations
[1]Whitney L Petrilli, et al. From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9. Cell Chem Biol. 2020 Jan 16;27 (1) :32-40.e3.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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