Sphingosine-1-phosphate (d17:1)

Sphingosine-1-phosphate d17:1 (D-erythro-Sphingosine-C17-1-phosphate) is a derivative of ceramide. Sphingosine-1-phosphate d17:1 can be used for the research of cancer[1].

Product Specifications

CAS Number

[474923-27-8]

Product Name Alternative

D-erythro-Sphingosine-C17-1-phosphate

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sphingosine-1-phosphate-d17-1.html

Purity

99.00

Solubility

0.3 M NaOH : 4 mg/mL (ultrasonic; warming)

Smiles

O=P(O)(O)OC[C@H](N)[C@H](O)/C=C/CCCCCCCCCCCC

Molecular Formula

C17H36NO5P

Molecular Weight

365.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang W, Xiang P, Chew WS, Torta F, Bandla A, Lopez V, Seow WL, Lam BWS, Chang JK, Wong P, Chayaburakul K, Ong WY, Wenk MR, Sundar R, Herr DR. Activation of sphingosine 1-phosphate receptor 2 attenuates chemotherapy-induced neuropathy. J Biol Chem. 2020 Jan 24;295 (4) :1143-1152. |[2]Wang W, et al. Activation of sphingosine 1-phosphate receptor 2 attenuates chemotherapy-induced neuropathy. J Biol Chem. 2020 Jan 24;295 (4) :1143-1152.