N-Palmitoyl-D-sphingomyelin

N-palmitoyl-D-sphingomyelin (sphingomyelin 16:0) is a component of LDL-carrying liposomes. N-palmitoyl-D-sphingomyelin can be used in colorectal cancer research[1][2].

Product Specifications

CAS Number

[6254-89-3]

Product Name Alternative

Sphingomyelin 16:0

UNSPSC

12352211

Hazard Statement

H301, H312, H330, H410

Target

Endogenous Metabolite; Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-palmitoyl-d-sphingomyelin.html

Purity

99.0

Solubility

Ethanol : 10 mg/mL (ultrasonic; warming)

Smiles

CCCCCCCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)COP(OCC[N+](C)(C)C)([O-])=O)=O

Molecular Formula

C39H79N2O6P

Molecular Weight

703.03

Precautions

H301, H312, H330, H410

References & Citations

[1]Holopainen JM, et al. Sphingomyelinase activity associated with human plasma low density lipoprotein. J Biol Chem. 2000 Jun 2;275 (22) :16484-9. |[2]Klutzny S, et al. Functional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death. Cell Death Dis. 2017 Mar 30;8 (3) :e2709.