Sphingosine (d17:1)

Sphingosine (d17:1) is a 17-carbon sphingosine found in human skin[1].

Product Specifications

CAS Number

[6918-48-5]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Natural Products

Related Pathways

Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sphingosine-d17-1.html

Purity

99.93

Solubility

DMF : 10 mg/mL (ultrasonic; warming) |DMSO : ≥ 2mg/mL

Smiles

OC[C@H](N)[C@H](O)/C=C/CCCCCCCCCCCC

Molecular Formula

C17H35NO2

Molecular Weight

285.47

Precautions

H302, H315, H319, H335

References & Citations

[1]Stewart ME, et al. Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines. J Invest Dermatol. 1995 Oct;105 (4) :613-8. |[2]Hong JH, et al. K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling. J Invest Dermatol. 2008 Sep;128 (9) :2166-78.|[3]Choi CH, et al. Sphingosine 1-phosphate and sphingosine kinase activity during chicken embryonic development. Arch Pharm Res. 2007 Apr;30 (4) :502-6.|[4]Zeng K, et al., Determination of endogenous sphingolipid content in stroke rats and HT22 cells subjected to oxygen-glucose deprivation by LC‒MS/MS. Lipids Health Dis. 2023 Jan 25;22 (1) :13.