EZH2-IN-5
Product Specifications
UNSPSC Description
EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively[1].
Target Antigen
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ezh2-in-5.html
Solubility
10 mM in DMSO
Smiles
CCN([C@H]1CC[C@@H](CC1)N(C)C)C2=C(C(C(NCC3=C(C=C(NC3=O)C)C)=O)=CC(Br)=C2)C
Molecular Weight
517.50
References & Citations
[1]Richard Chesworth, et al. Substituted benzene compounds. WO2012142513A1
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141566/EZH2-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141566/
Clinical Information
No Development Reported
CAS Number
1403258-69-4
Curated Selection
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