(R) -GNE-274
(R) -GNE-274 is a enantiomer of GNE-274. GNE-274 is a non-degrader that is structurally related to GDC-0927 (estrogen receptor degrader) [1].
Product Specifications
UNSPSC
12352005
Target
Drug Isomer
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/r-gne-274.html
Solubility
10 mM in DMSO
Smiles
CCCN1CC(C1)COC2=CC=C([C@H]3OC4=CC=C(C=C4C(C)=C3C5=CC(O)=CC=C5)O)C=C2
Molecular Formula
C29H31NO4
Molecular Weight
457.56
References & Citations
[1]Guan J, et al. Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility. Cell. 2019 Aug 8;178 (4) :949-963.e18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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