TLR8 agonist 2 (hydrochloride)
Product Specifications
UNSPSC Description
TLR8 agonist 2 hydrochloride is a potent and selective TLR8 agonist with an EC50 of 3 nM for human TLR8. TLR8 agonist 2 hydrochloride shows less active against human TLR7 (EC50 of 33.33 μM)[1].
Target Antigen
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tlr8-agonist-2-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
CCCC[C@@](CC1=NN=CN1)(C)NC2=NC(N)=NC3=C2C=CN=C3.[x].Cl
References & Citations
[1]Zhe Cai, et al. Tlr8 agonist. WO2020057604A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141454A/TLR8-agonist-2-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141454A/
Clinical Information
No Development Reported
CAS Number
2412937-65-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
