TLR8 agonist 2
TLR8 agonist 2 is a potent and selective TLR8 agonist with an EC50 of 3 nM for human TLR8. TLR8 agonist 2 shows less active against human TLR7 (EC50 of 33.33 μM) [1].
Product Specifications
CAS Number
[2412937-64-3]
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tlr8-agonist-2.html
Solubility
10 mM in DMSO
Smiles
CCCC[C@@](CC1=NN=CN1)(C)NC2=NC(N)=NC3=C2C=CN=C3
Molecular Formula
C16H22N8
Molecular Weight
326.40
References & Citations
[1]Zhe Cai, et al. Tlr8 agonist. WO2020057604A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141454/TLR8-agonist-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141454/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7; TLR8
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