Chloroacetamido-PEG4-NHS ester
Chloroacetamido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[1353011-95-6]
UNSPSC
12352005
Hazard Statement
H302-H317
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/chloroacetamido-peg4-nhs-ester.html
Solubility
10 mM in DMSO
Smiles
O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCNC(CCl)=O
Molecular Formula
C17H27ClN2O9
Molecular Weight
438.86
Precautions
P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; PEG Linkers
Available Sizes
Curated Selection
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