N-Succinimidyl 3- (Bromoacetamido) propionate
N-Succinimidyl 3- (Bromoacetamido) propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Succinimidyl 3- (Bromoacetamido) propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [2].
Product Specifications
CAS Number
57159-62-3
Product Name Alternative
3- (2-Bromoacetamido) propanoic acid NHS ester
UNSPSC
12352203
Hazard Statement
H315-H319-H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-succinimidyl-3-bromoacetamido-propionate.html
Solubility
10 mM in DMSO
Smiles
O=C(ON1C(CCC1=O)=O)CCNC(CBr)=O
Molecular Formula
C9H11BrN2O5
Molecular Weight
307.10
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; Cleavable Linker; PEG Linkers
Available Sizes
Frequently Asked Questions
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