C-NH-Boc-C-Bis- (C1-PEG1-PFP)
C-NH-Boc-C-Bis- (C1-PEG1-PFP) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[1807521-01-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-nh-boc-c-bis-c1-peg1-pfp.html
Solubility
10 mM in DMSO
Smiles
O=C(CCOCC(COCCC(OC(C(F)=C(F)C(F)=C1F)=C1F)=O)NC(OC(C)(C)C)=O)OC(C(F)=C(F)C(F)=C2F)=C2F
Molecular Formula
C26H23F10NO8
Molecular Weight
667.45
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; PEG Linkers
Curated Selection
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