TCO-PEG3-amide-C3-triethoxysilane
Product Specifications
UNSPSC Description
TCO-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. TCO-PEG3-amide-C3-triethoxysilane is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tco-peg3-amide-c3-triethoxysilane.html
Solubility
10 mM in DMSO
Smiles
CCO[Si](OCC)(OCC)CCCNC(CCOCCOCCOCCNC(OC1CCC/C=C\CC1)=O)=O
Molecular Weight
576.80
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141185/TCO-PEG3-amide-C3-triethoxysilane-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141185/
Clinical Information
No Development Reported
CAS Number
2250217-32-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6226068-01 0.1 mL
Thymidylate Synthase (dTMP synthase, TMS, TS, TSase, TYMS Protein, Tyms thymidylate synthetase) (BSA & Azide Free) (MaxLight 650)
Ask
View Details 
MBS6226068-02 5x 0.1 mL
Thymidylate Synthase (dTMP synthase, TMS, TS, TSase, TYMS Protein, Tyms thymidylate synthetase) (BSA & Azide Free) (MaxLight 650)
Ask
View Details