TCO-PEG8-acid
Product Specifications
UNSPSC Description
TCO-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. TCO-PEG8-acid is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tco-peg8-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
Molecular Weight
593.70
References & Citations
[1]Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141161/TCO-PEG8-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141161/
Clinical Information
No Development Reported
CAS Number
2353410-03-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6210891-01 0.1 mL
COG7 (Conserved Oligomeric Golgi Complex Component 7, COG Complex Subunit 7, Component of Oligomeric Golgi Complex 7, CDG2E, UNQ3082/PRO10013) (MaxLight 550)
Ask
View Details MBS6210891-02 5x 0.1 mL
COG7 (Conserved Oligomeric Golgi Complex Component 7, COG Complex Subunit 7, Component of Oligomeric Golgi Complex 7, CDG2E, UNQ3082/PRO10013) (MaxLight 550)
Ask
View Details