Fmoc-PEG3-Ala-Ala-Asn (Trt) -PAB
Fmoc-PEG3-Ala-Ala-Asn (Trt) -PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
2055042-69-6
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-peg3-ala-ala-asn-trt-pab.html
Solubility
10 mM in DMSO
Smiles
O=C(C[C@H](NC([C@H](C)NC([C@H](C)NC(CCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C13)=O)=O)=O)=O)C(NC4=CC=C(CO)C=C4)=O)NC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7
Molecular Formula
C60H66N6O11
Molecular Weight
1047.20
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker
Frequently Asked Questions
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