OPSS-Val-Cit-PAB-PNP
Product Specifications
UNSPSC Description
OPSS-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Target Antigen
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/opss-val-cit-pab-pnp.html
Solubility
10 mM in DMSO
Smiles
CC(C)[C@@H](C(N[C@H](C(NC1=CC=C(COC(OC2=CC=C([N+]([O-])=O)C=C2)=O)C=C1)=O)CCCNC(N)=O)=O)NC(CCSSC3=NC=CC=C3)=O
Molecular Weight
741.83
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141145/OPSS-Val-Cit-PAB-PNP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141145/
Clinical Information
No Development Reported
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