MC(C5)-Val-Cit
Product Specifications
UNSPSC Description
MC(C5)-Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Target Antigen
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-c5-val-cit.html
Solubility
10 mM in DMSO
Smiles
OC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC(CCCCN1C(C=CC1=O)=O)=O)=O)=O
Molecular Weight
452.50
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141143/MC-C5-Val-Cit-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141143/
Clinical Information
No Development Reported
CAS Number
2504147-59-3
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