LG-PEG10-click-DBCO-Oleic

LG-PEG10-click-DBCO-Oleic is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/lg-peg10-click-dbco-oleic.html

Solubility

10 mM in DMSO

Smiles

O=C(CCNC(CCCCCCC/C=C\CCCCCCCC)=O)N1C2=CC=CC=C2C(N=NN3CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC([C@@H]([C@H](C(O[C@H]4[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O4)[C@@H](CO)O)O)O)=O)=C3C5=CC=CC=C5C1

Molecular Formula

C70H114N6O23

Molecular Weight

1407.68

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562