NHS-PEG4- (m-PEG12) 3-ester

NHS-PEG4- (m-PEG12) 3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nhs-peg4-m-peg12-3-ester.html

Solubility

10 mM in DMSO

Smiles

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCOCC(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)NC(CCOCCOCCOCCOCCNC(CCCC(ON1C(CCC1=O)=O)=O)=O)=O)=O

Molecular Formula

C108H206N6O52

Molecular Weight

2420.80

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562