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Biotin-PEG4-Dde-TAMRA-PEG3-Azide

Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[2353409-56-8]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/biotin-peg4-dde-tamra-peg3-azide.html

Solubility

10 mM in DMSO

Smiles

[O-]C(C(C=C(C(NCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCC(NCCCN/C(CCOCCOCCOCCOCCNC(CCCC[C@H]1[C@](NC2=O)([H])[C@](N2)([H])CS1)=O)=C(C3=O)\C(CC(C)(C)C3)=O)=O)=O)=O)C=C4)=C4C5=C(C=CC(N)=C6)C6=[O+]C7=C5C=CC(N(C)C)=C7)=O

Molecular Formula

C69H96N12O17S

Molecular Weight

1397.64

References & Citations

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Isoform

Cleavable Linker

Curated Selection

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