Carboxyrhodamine 110-PEG3-Azide
Product Specifications
UNSPSC Description
Carboxyrhodamine 110-PEG3-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Carboxyrhodamine 110-PEG3-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carboxyrhodamine-110-peg3-azide.html
Solubility
10 mM in DMSO
Smiles
[O-]C(C1=CC(C(NCCOCCOCCOCCN=[N+]=[N-])=O)=CC=C1C2=C(C=CC(N)=C3)C3=[O+]C4=C2C=CC(N)=C4)=O.[O-]C(C5=CC=C(C(NCCOCCOCCOCCN=[N+]=[N-])=O)C=C5C6=C(C=CC(N)=C7)C7=[O+]C8=C6C=CC(N)=C8)=O
Molecular Weight
574.60
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141090/Carboxyrhodamine-110-PEG3-Azide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141090/
Clinical Information
No Development Reported
CAS Number
1536327-95-3
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