Carboxyfluorescein-PEG12-NHS
Carboxyfluorescein-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[2246595-66-2]
UNSPSC
12171500
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Dye Reagents
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carboxyfluorescein-peg12-nhs.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C2(O3)C(C=CC=C4)=C4C3=O)C(OC5=C2C=CC(O)=C5)=C1.O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC([D1])=O)ON6C(CCC6=O)=O
Molecular Formula
C52H68N2O22
Molecular Weight
1073.10
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Isoform
PEG Linkers
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