Fluorescein-PEG6-NHS ester

Fluorescein-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[1818294-35-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fluorescein-peg6-nhs-ester.html

Purity

95.00

Solubility

DMSO : 4.17 mg/mL (ultrasonic)

Smiles

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCNC(NC2=CC3=C(C4(C5=C(OC6=C4C=CC(O)=C6)C=C(O)C=C5)OC3=O)C=C2)=S

Molecular Formula

C40H45N3O15S

Molecular Weight

839.86

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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