N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7
Product Specifications
UNSPSC Description
N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-n-bis-azide-peg3-chlorocyclohexenyl-cy7.html
Solubility
10 mM in DMSO
Smiles
CC1(C)C(/C=C/C2=C(Cl)/C(CCC2)=C\C=C3N(CCOCCOCCOCCN=[N+]=[N-])C4=C(C=CC=C4)C/3(C)C)=[N+](CCOCCOCCOCCN=[N+]=[N-])C5=C1C=CC=C5.[Cl-]
Molecular Weight
893.94
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141079/N-N-bis-azide-PEG3-chlorocyclohexenyl-Cy7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141079/
Clinical Information
No Development Reported
CAS Number
2107273-84-5
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