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N, N'-bis- (azide-PEG3) -chlorocyclohexenyl Cy7

Selected Variant

HY-141079

Size: 1 Each

N, N'-bis- (azide-PEG3) -chlorocyclohexenyl Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N, N'-bis- (azide-PEG3) -chlorocyclohexenyl Cy7 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

2107273-84-5

UNSPSC

12352005

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-n-bis-azide-peg3-chlorocyclohexenyl-cy7.html

Solubility

10 mM in DMSO

Smiles

CC1(C)C(/C=C/C2=C(Cl)/C(CCC2)=C\C=C3N(CCOCCOCCOCCN=[N+]=[N-])C4=C(C=CC=C4)C/3(C)C)=[N+](CCOCCOCCOCCN=[N+]=[N-])C5=C1C=CC=C5.[Cl-]

Molecular Formula

C46H62Cl2N8O6

Molecular Weight

893.94

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

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