N- (m-PEG4) -N'- (Biotin-PEG2-amido-PEG4) -Cy5

N- (m-PEG4) -N'- (Biotin-PEG2-amido-PEG4) -Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2107273-78-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-m-peg4-n-biotin-peg2-amido-peg4-cy5.html

Solubility

10 mM in DMSO

Smiles

CC1(C)C(/C=C/C=C/C=C2N(CCOCCOCCOCCOCCC(NCCOCCOCCNC(CCCC[C@H]3SC[C@@]([C@@]3([H])N4)([H])NC4=O)=O)=O)C(C=CC=C5)=C5C/2(C)C)=[N+](CCOCCOCCOCCOC)C6=CC=CC=C61.[Cl-]

Molecular Formula

C61H93ClN6O13S

Molecular Weight

1185.94

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562