N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5
Product Specifications
CAS Number
2107273-74-3
UNSPSC Description
N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
PROTAC Linkers
Type
Dye Reagents
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-azide-peg3-n-mal-peg4-cy5.html
Solubility
10 mM in DMSO
Smiles
CC1(C)C(/C=C/C=C/C=C2N(CCOCCOCCOCCN=[N+]=[N-])C3=C(C=CC=C3)C/2(C)C)=[N+](CCOCCOCCOCCOCCC(NCCN4C(C=CC4=O)=O)=O)C5=C1C=CC=C5.[Cl-]
Molecular Weight
962.57
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Frequently Asked Questions
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