N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5
Product Specifications
UNSPSC Description
N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-azide-peg3-n-amine-c3-amide-peg4-cy5.html
Solubility
10 mM in DMSO
Smiles
CC1(C)C(/C=C/C=C/C=C2N(CCOCCOCCOCCOCCC(NCCCN)=O)C3=C(C=CC=C3)C/2(C)C)=[N+](CCOCCOCCOCCN=[N+]=[N-])C4=C1C=CC=C4.[Cl-]
Molecular Weight
896.55
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141065/N-azide-PEG3-N-Amine-C3-Amide-PEG4-Cy5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141065/
Clinical Information
No Development Reported
CAS Number
2107273-70-9
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