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N- (m-PEG4) -N'- (m-PEG4) -O- (m-PEG4) -O'- (propargyl-PEG4) -Cy5

N- (m-PEG4) -N'- (m-PEG4) -O- (m-PEG4) -O'- (propargyl-PEG4) -Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N- (m-PEG4) -N'- (m-PEG4) -O- (m-PEG4) -O'- (propargyl-PEG4) -Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

2107273-54-9

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-m-peg4-n-m-peg4-o-m-peg4-o-propargyl-peg4-cy5.html

Solubility

10 mM in DMSO

Smiles

COCCOCCOCCOCC[N+]1=C(/C=C/C=C/C=C2N(CCOCCOCCOCCOC)C3=C(C=C(OCCOCCOCCOCCOC)C=C3)C\2(C)C)C(C)(C)C4=C1C=CC(OCCOCCOCCOCCOCC#C)=C4.[Cl-]

Molecular Formula

C63H99ClN2O18

Molecular Weight

1207.92

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Frequently Asked Questions

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