N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5
Product Specifications
UNSPSC Description
N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-m-peg4-n-m-peg4-o-m-peg4-o-propargyl-peg4-cy5.html
Solubility
10 mM in DMSO
Smiles
COCCOCCOCCOCC[N+]1=C(/C=C/C=C/C=C2N(CCOCCOCCOCCOC)C3=C(C=C(OCCOCCOCCOCCOC)C=C3)C\2(C)C)C(C)(C)C4=C1C=CC(OCCOCCOCCOCCOCC#C)=C4.[Cl-]
Molecular Weight
1207.92
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-141053/N-m-PEG4-N-m-PEG4-O-m-PEG4-O-propargyl-PEG4-Cy5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-141053/
Clinical Information
No Development Reported
CAS Number
2107273-54-9
Curated Selection
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