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N-PEG3-N'-(propargyl-PEG4)-Cy5

Product Specifications

UNSPSC Description

N-PEG3-N'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-PEG3-N'-(propargyl-PEG4)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-peg3-n-propargyl-peg4-cy5.html

Solubility

10 mM in DMSO

Smiles

CC1(C)C(/C=C/C=C/C=C2N(CCOCCOCCOCCOCC#C)C3=C(C=CC=C3)C/2(C)C)=[N+](CCOCCOCCO)C4=C1C=CC=C4.[Cl-]

Molecular Weight

737.36

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-141050/N-PEG3-N-propargyl-PEG4-Cy5-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-141050/

Clinical Information

No Development Reported

CAS Number

2107273-06-1

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