N-PEG3-N'- (propargyl-PEG4) -Cy5
N-PEG3-N'- (propargyl-PEG4) -Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-PEG3-N'- (propargyl-PEG4) -Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[2107273-06-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-peg3-n-propargyl-peg4-cy5.html
Solubility
10 mM in DMSO
Smiles
CC1(C)C(/C=C/C=C/C=C2N(CCOCCOCCOCCOCC#C)C3=C(C=CC=C3)C/2(C)C)=[N+](CCOCCOCCO)C4=C1C=CC=C4.[Cl-]
Molecular Formula
C42H57ClN2O7
Molecular Weight
737.36
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
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SH3RF2 (SH3 Domain-containing RING Finger Protein 2, Putative E3 Ubiquitin-protein Ligase SH3RF2, Heart Protein Phosphatase 1-binding Protein, HEPP1, Protein Phosphatase 1 Regulatory Subunit 39, PPP1R39, POSHER, RING Finger Protein 158, RNF158) (MaxLight
SH3RF2 (SH3 Domain-containing RING Finger Protein 2, Putative E3 Ubiquitin-protein Ligase SH3RF2, Heart Protein Phosphatase 1-binding Protein, HEPP1, Protein Phosphatase 1 Regulatory Subunit 39, PPP1R39, POSHER, RING Finger Protein 158, RNF158) (MaxLight