Bis- (N, N'-PEG4-NHS ester) -Cy5

Bis- (N, N'-PEG4-NHS ester) -Cy5 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2107273-48-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bis-n-n-peg4-nhs-ester-cy5.html

Solubility

10 mM in DMSO

Smiles

CC(C1=CC=CC=C1N/2CCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O)(C)C2=C/C=C/C=C/C4=[N+](CCOCCOCCOCCOCCC(ON5C(CCC5=O)=O)=O)C(C=CC=C6)=C6C4(C)C.[Cl-]

Molecular Formula

C55H73ClN4O16

Molecular Weight

1081.64

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers

Curated Selection

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