Bis- (N, N'-PEG4-NHS ester) -Cy5
Bis- (N, N'-PEG4-NHS ester) -Cy5 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[2107273-48-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bis-n-n-peg4-nhs-ester-cy5.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=CC=C1N/2CCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O)(C)C2=C/C=C/C=C/C4=[N+](CCOCCOCCOCCOCCC(ON5C(CCC5=O)=O)=O)C(C=CC=C6)=C6C4(C)C.[Cl-]
Molecular Formula
C55H73ClN4O16
Molecular Weight
1081.64
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Curated Selection
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