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N- (m-PEG4) -N'- (PEG2-NHS ester) -Cy5

N- (m-PEG4) -N'- (PEG2-NHS ester) -Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2107273-28-7]

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Dye Reagents

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-m-peg4-n-peg2-nhs-ester-cy5.html

Purity

99.74

Solubility

Methanol : 12.5 mg/mL (ultrasonic)

Smiles

CC1(C)C(/C=C/C=C/C=C2N(CCOCCOCCC(ON3C(CCC3=O)=O)=O)C(C=CC=C4)=C4C/2(C)C)=[N+](CCOCCOCCOCCOC)C5=CC=CC=C51.[Cl-]

Molecular Formula

C45H60ClN3O10

Molecular Weight

838.43

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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