N-methyl-N'-methyl-O- (m-PEG4) -O'- (acid-PEG5) -Cy5
N-methyl-N'-methyl-O- (m-PEG4) -O'- (acid-PEG5) -Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-methyl-n-methyl-o-m-peg4-o-acid-peg5-cy5.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC(OCCOCCOCCOCCOCCOCCC(O)=O)=CC=C1N/2C)(C)C2=C/C=C/C=C/C3=[N+](C)C(C=CC(OCCOCCOCCOCCOC)=C4)=C4C3(C)C.[Cl-]
Molecular Formula
C49H73ClN2O13
Molecular Weight
933.56
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Curated Selection
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